Bud Abbott and Lou Costello

Abbott and Costello launched their own weekly show October 8, 1942, sponsored by Camel cigarettes. The Abbott and Costello Show mixed comedy with musical interludes. Ken Niles was the show's longtime announcer, doubling as an exasperated foil to Abbott and Costello's mishaps (and often fuming in character as Costello routinely insulted his on-air wife). Niles was succeeded by Michael Roy, with announcing chores also handled over the years by Frank Bingman and Jim Doyle. The show went through several orchestras during its radio life, including those of Ennis, Charles Hoff, Matty Matlock, Jack Meakin, Will Osborne, Freddie Rich, Leith Stevens, and Peter van Steeden. The show's writers included Howard Harris, Hal Fimberg, Parke Levy, Don Prindle, Eddie Cherkose (later known as Eddie Maxwell), Leonard Stern, Martin Ragaway, Paul Conlan, and Eddie Forman, as well as producer Martin Gosch. Sound effects were handled primarily by Floyd Caton.

In 1947 Abbott and Costello moved the show to ABC (the former NBC Blue Network). During their time on ABC, the duo also hosted a 30-minute children's radio program (The Abbott and Costello Children's Show), which aired Saturday mornings, featuring child vocalist Anna Mae Slaughter and child announcer Johnny McGovern.

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